Two goals from Justice and Bright Enchill ensured the home team bag the maximum point.
Blay, who has earned his first Black Stars call up put Medeama ahead through the spot-kick.
He scored brilliantly from the spot after Abass Mohammed was adjudged to have been fouled in the box.
Left-back Bright Enchil scored his debut goal for the Mauve and Yellows after he lashed the ball into the bottom corner.
However, it’s the lead up to the goal that has sent fans waxing lyrical after Rashid Nortey exquisite pass found Enchil who drilled home the insurance goal.
Medeama spurned several chances especially in the second half with Ebenezer Ackahbi, Joseph Tetteh-Zutah and Abass Mohammed the worst culprit.
The home team will have to count their stars after the visitors improved drastically in the second half.
The Hunters introduced Amankona but it was Duodu who stole the show for their team.
Medeama have now amassed 20 points from 14 games and travel to Elmina to battle Sharks in their next encounter.
Bechem United are still two points above the Tarkwa-based side on 22 points.